In the early 1900s, on a small farm in La Porte, Indiana, Norwegian immigrant Belle Gunness used strychnine to poison her boyfriends before feeding their remains to the hogs.
Gunness's motive was to collect life insurance, cash and other valuables from her victims.
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Diane Downs – On May 19, 1983, in Springfield, Oregon, Downs shot her three children, killing one of them.
She was pursuing a romantic relationship with a married man who didn't want children and refused to leave his wife. Martha Wise – In Medina County, Ohio in 1925, Wise, who was mentally ill, poisoned three of her family members to death and injured more than a dozen with arsenic.
After a three-year hiatus, the show resumed production in 2008 and began airing on the Investigation Discovery channel as a regularly scheduled series.