Sedaris is also a playwright, having written with his sister, actress Amy Sedaris, several plays under the name "The Talent Family".
These include Stump the Host (1993), Stitches (1994), and The Little Frieda Mysteries (1997).
All were produced and presented by Meryl Vladimer when she was the artistic director of "the CLUB" at La Ma Ma, E. C., and The Book of Liz (2002) was produced by Ania A. Sedaris also co-authored Incident at Cobbler's Knob, presented and produced by David Rockwell at the Lincoln Center Festival.
He moved to Chicago in 1983 and graduated from the School of the Art Institute of Chicago in 1987.
(He did not attend Princeton University, although he spoke fondly of doing so in "What I Learned", a comic baccalaureate address delivered at Princeton in June 2006.) While working odd jobs across Raleigh, Chicago, and New York City, Sedaris was discovered in a Chicago club by radio host Ira Glass; Sedaris was reading a diary he had kept since 1977.
Glass asked him to appear on his weekly local program, The Wild Room.
Sedaris' success on The Wild Room led to his National Public Radio debut on December 23, 1992, when he read a radio essay on Morning Edition titled "Santa Land Diaries", which described his purported experiences as an elf at Macy's department store during Christmas in New York.
Subsequently, in the wake of a controversy involving Mike Daisey's dramatizing and embellishing his personal experiences at Chinese factories, during an excerpt from his theatrical monologue for This American Life, new attention has been paid to the veracity of Sedaris' nonfiction stories.